Hotel Sant' Anna

Hotels
Independent
9.4 (136 reviews)
via borgo pio 134, Rome, RM, 193 , Rome , IT

Facilities

Free WiFi
24-hour front desk
Garden
Luggage storage
Concierge service
Wheelchair accessible
Breakfast available (surcharge)
Smoke-free property

Review Highlights

Pros:
Great location
Friendly staff
Comfortable stay
Clean facilities
Cons:
Annoyance from street hawkers

Categories

Cleanliness
9.25
The hotel is nice, clean, quiet, and comfortable.
Service
9.75
The staff was friendly and helpful. Extremely nice and helpful staff.
Location
9.65
Great location close to Vatican City, metro, and many restaurants.
Room Quality
9.15
Room was very quaint and cleaned every day.
Amenities
9.25
Nice breakfast in the morning.
Value for Money
9.25
Great value for the location and comfort provided.
Food and Beverage
9.05
Breakfast was great.
Overall Experience
9.85
Our visit was nothing short of amazing.
* This sentiment is summarized by AI based on user reviews.
Updated at: 2026-01-06 20:24

Property Description

Discover the charm of Hotel Sant' Anna, your perfect gateway to the heart of Rome's historic treasures.

Exceptional Location
Nestled just a 4-minute stroll from St. Peter's Square and St. Peter's Basilica, enjoy unparalleled access to the city's iconic landmarks, including the Vatican Museums and Sistine Chapel, all within walking distance.

Comfort and Convenience
Our 20 well-appointed guestrooms feature minibars, flat-screen televisions, and complimentary wireless internet access to keep you connected during your stay. Experience the luxury of modern amenities designed for your ultimate comfort.

Delightful Dining
Kickstart your day with a flavorful buffet breakfast served daily from 7:00 AM to 10:00 AM. Our concierge services are also at your disposal, ensuring all your needs are met while you explore the historic surroundings.

Experience the allure of Rome like never before—book your stay at Hotel Sant' Anna today!

Important information:

  • All guests, including children, must be present at check-in and show their government-issued photo ID card or passport.
  • Cash transactions at this property cannot exceed EUR 5000, due to national regulations. For further details, please contact the property using information in the booking confirmation.
  • Only registered guests are allowed in the guestrooms.

Check-in and check-out hours:
Check-out: 10:30 AM
Airport code: ROM

Property Policies

  • Pets

    Pets not allowed

  • Children and extra beds

    No rollaway/extra beds available

  • Guest type

    Essential workers only - NO

  • Accessibility

    No elevators

  • General

    Professional property host/manager

Location

Guest Reviews

9.4
Based on 136 reviews
Cleanliness: 9.25
Service: 9.75
Location: 9.65
Room Quality: 9.15
Amenities: 9.25
Value for Money: 9.25
Food and Beverage: 9.05
Overall Experience: 9.85
P
Patricia and Charles
10
Pros:

Hotel Sant ‘Anna is in a great location close to Vatican City, the metro, and many restaurants & tourist shops. We were comfortable and had space for our family of four. The hotel is nice, clean, quiet, and comfortable. The staff was friendly and helpful.
The only downside was the annoyance of having to walk past the restaurants hawkers (with their high-pressure sales pitch to lure in you and others) who on the street in front of the hotel, but that was the trade-off for convenience.

2025-09-27 via Nuitee
C
Cherry family
10
Pros:

Very friendly staff. Free breakfast with the stay.

2025-09-25 via Nuitee
S
Stephen family
10
Pros:

Wonderful location, very helpful service and staff!

2025-09-22 via Nuitee
R
reelrush530 Family Mallorytown, Ontario
10
Super Clean, Great Location, Pleasant Staff
Pros:

The cleanest hotel I have ever stayed in. Just spotless. The location is great, especially if you want to go to the Vatican but also for the restaurants and bars every where. Staff is there 24/7 and very pleasant and helpful.

2025-09-16 via Tripadvisor
B
Barry A family
10
Pros:

Extremely nice and helpful staff. Room was very quaint and great access to a lot of tourist spots within a mile. Room was cleaned every day. Highly recommend

2025-09-11 via Nuitee
J
John
10
Pros:

All of the staffs were amazing. We stayed for 5 nights and no complaints at all. Breakfast was great. This is the hotel

2025-08-23 via Nuitee
M
Manions NONE Bardstown, Kentucky
10
Perfect base for a relaxed stay in Rome
Pros:

This was our 4th stay at Hotel Sant'Anna. Obviously, we love this place. The location is perfect. Around the corner from St. Peter's and the Vatican Museums. Castel Gandolfo is at the other end of the street. You're a very comfortable stroll from Piazza Navonna, Trastevere and plenty of other sights. Less than 5 minutes to the nearest taxi stand, and maybe 7 minutes to the nearest Metro stop. The street in front of the hotel is pedestrian-only and filled with restaurants, gelato places, and small shops.

The staff is very friendly and always helpful with any requests before and during your stay. The breakfast is just what we need in a nice setting. The rooms are immaculate and a good size. There's a tastefully decorated sitting area in the hotel for when you're worn out from sightseeing and just want to sit and relax.

And remember to say hello to Nina, the owner's awesome puppy who hangs out in front most mornings!

2025-08-07 via Tripadvisor
W
W4273ZYpeterm Couples
10
When in Rome........do as we do ....enjoy Sant'Anna
Pros:

I agree with the the many positive reviews. If you don't need a gym or a pool or a glitzy restaurant but a friendly, elegant,well-run base very close to the Vatican, this is ideal. This was our second visit and we would not hesitate to return. The lack of an evening restaurant is not a problem. We enjoyed a very good dinner at Arlu which is right next door.

2025-07-29 via Tripadvisor
D
DIANE
10
Pros:

This hotel is very quaint near everything to walk. The front desk was very nice and helpful and polite. Nice breakfast in the morning too. I would definitely stay here again.

2025-07-24 via Nuitee
J
John
10
Best Hotel to Visit Rome!
Pros:

From the moment we arrived atthe hotel until we left, our visit was nothing short of amazing. Walking distances to most every site and point of intrest!

2025-07-12 via Nuitee
2
263margaretk Family Hillsboro, Oregon
10
Lovely hotel near the Vatican
Pros:

My room was lovely, comfortable and immaculate. The small elevator was a welcome convenience. Breakfast was European plus American items such as nice made to order eggs. Breakfast area was comfortable and is adjacent to a small courtyard with tables. Communication with the staff prior to visitng was excellent and they were very helpful with directions, taxi, recommendations, etc. The street in front of the hotel is pedestrian -only with cafes occupying the space. Many dining options, shops, and of course the Vatican are an easy walk from the hotel. I highly recommend.

2025-07-04 via Tripadvisor
A
aiw-nj Solo travel
10
Wonderful Stay!
Pros:

I stayed at this hotel for the second time and it was better than ever. Friendly, excellent service, comfortable room and perfectly situated for my needs. Wonderful staff.

2025-06-29 via Tripadvisor
S
Susan
10
Pros:

Great location, amazing staff!

2025-06-24 via Nuitee
L
Lynn friends
10
Pros:

Great little hotel very near the Vatican. Very clean and typically Roman. Lovely.

2025-06-10 via Nuitee
C
Cathy partner
10
Pros:

The staff was outstanding. Very helpful and friendly. Location very walkable, close to Vatican and also short walk to subway, etc the room was comfortable and shower had good water pressure.

2025-06-09 via Nuitee
T
theresacatlin Solo travel Mariposa, California
10
Highly recommended!
Pros:

This hotel was perfect for me. The pedestrian-only street is a huge plus. It is literally lined with restaurants, gelato places and souvenir shops. Dinner was a cinch, which was very much appreciated after long days of sightseeing. And best of all - it made this location quiet. I did have a room at the back of the hotel. If you're a light sleeper like me, you might want to ask for that.

The location was ideal for me. It was only a 10 min walk to the meeting spot for my 7:15 AM Vatican Museum / Sistine Chapel / St. Peter's tour. It's close to Castel Sant'Angelo and a 2 mile walk to Trastevere, where I had a food tour. Walking "home" at dusk from Trastevere along the Tiber River was memorable.
I also walked to and from the Spanish Steps from this hotel - 6 miles round trip and full of unforgettable sites.

The hotel staff was helpful, friendly and considerate. This was my sixth hotel in Italy and I found my room to be one of the best I stayed in: it was spotless, and the bed was very comfortable. I appreciated that there was ample open shelving, a good closet with lockbox, plus a little desk. The room was not large, but I didn't need that. I found it cozy and comfortable. I also appreciated that I could open the windows for fresh air.
The bathroom was the best I'd experienced during my 2 1/2 weeks traveling in Italy; it was attractive, well equipped, with great lighting and counter space.

The breakfast was ample and varied in the attractively decorated lower level. I highly recommend it.

Out of all the hundreds of hotels in Rome, I am so glad I chose this one. I would choose it again for its location, cleanliness, amenities and the helpfulness of the staff.

2025-06-05 via Tripadvisor
A
Alfonso family_with_children
8
Pros:

The facilities are good, staff amazing, the location is unbeatable if you are looking to stay near the Vatican. The Breakfast is okay. In others words, highly recomended hotel.

2025-06-03 via Nuitee
R
Ricardo
10
Pros:

Excelent hotel for stay in the best place of Rome

2025-05-30 via Nuitee
L
Luis
10
Great experience
Pros:

Best of experience ever! Nice and comfortable room and close to Vatican. I will back for sure !

2025-05-22 via Nuitee
M
Margaret
10
Pros:

The staff was wonderful and the room was beautiful. I do not not if the room I had was an upgrade, but either way it was beautiful. I'm booking this hotel in an upcoming stay.

2025-05-22 via Nuitee