Residence Inn by Marriott Durham Duke University Medical Center Area

Hotels
Residence Inn
9 (240 reviews)
1108 West Main Street , Durham , us

Paid
Children allowed

Facilities

Fitness facilities
WiFi available
Free WiFi
Parking
Non-smoking rooms
Air conditioning
Fitness center
24-hour front desk
Business center
Heating
See all facilities

Review Highlights

Pros:
Friendly and attentive staff
Great location near the hospital
Cons:
Breakfast quality needs improvement
Lumpy bed in the room

Categories

Cleanliness
8.33
The place is CLEAN, but the bed was super lumpy.
Service
9.8
Service was highly praised, with staff being friendly, attentive, and accommodating.
Location
9.34
Super close to the hospital, which was ideal for guests attending a medical event.
Room Quality
8.29
Rooms are spacious, but one review mentioned a lumpy bed.
Amenities
9.32
Breakfast included; hot and tasty, with fresh coffee always available.
Value for Money
9.28
Overall a great place to stay given the circumstances and services offered.
Food and Beverage
8.33
Breakfast needs improvement; specific dislike of pre-seasoned eggs and turkey sausage.
Overall Experience
9.3
A warm, supportive atmosphere during a stressful time was greatly appreciated.
* This sentiment is summarized by AI based on user reviews.
Updated at: 2026-01-06 22:10

Property Description

Modern Amenities
Residence Inn by Marriott Durham Duke University Medical Center Area offers free WiFi, complimentary breakfast, and fully equipped kitchens in every room.

Convenient Facilities
Guests can enjoy a fitness centre, 24-hour reception, and on-site mini-market. Additional perks include grocery deliveries, meeting rooms, and free parking.

Prime Location
Located near popular attractions like Brightleaf District and Durham Performing Arts Center, with Duke University Hospital just a short drive away. Raleigh-Durham International Airport is conveniently close for travelers.

Ready to experience comfort and convenience at Residence Inn by Marriott Durham Duke University Medical Center Area? Book your stay now!

Important information:

Guests are required to show a photo ID and credit card upon check-in. Please note that all Special Requests are subject to availability and additional charges may apply.
A deposit may be required at the property.

Check-in and check-out hours:
Check-out: 12:00 PM
Airport code: RDU

Location

Guest Reviews

9
Based on 240 reviews
Cleanliness: 8.33
Service: 9.8
Location: 9.34
Room Quality: 8.29
Amenities: 9.32
Value for Money: 9.28
Food and Beverage: 8.33
Overall Experience: 9.3
R
rajivvaidb Solo travel
10
Great gem of a hotel with lovely staff!
Pros:

Decent breakfast included and Kenneth made some great egg dishes like the Quiche etc so that was a great add on!
The reception staff was kind and helpful. Brad who ran the shuttle service was a star and probably the best amenity that this hotel offers compared to any other is the free shuttle service within a 3 mile radius - great for guests coming in for events without a car! Brad also helped me bring a bag in to the conference at Duke I was attending as I had forgotten it at the hotel.
Comfortable and spacious rooms. Good wifi. Nice and clean! Only issue was there is only one elevator so sometimes during busy hours there can be a wait! Location is not central central but a 10-20 min walk to downtown central Central Area!

2026-08-08 via Tripadvisor
M
michellewF6596EP Family
10
Great hotel with wonderful hot breakfast buffet
Pros:

Wonderful breakfast included and clean, nice rooms. Many thanks to Ken who made more waffle mix when we were almost out and was so kind and helpful.

2026-08-08 via Tripadvisor
T
Trek10355366785 Family
10
Enjoyable experience!
Pros:

Love it here!
KW outdid himself with the phenomenal breakfast. His warm and welcoming personality was the icing on the cake.
Looking forward to our next visit and hope to see KW again.

2026-08-08 via Tripadvisor
M
marthatM5630SB Family
10
Visiting Duke
Pros:

Ken was so hopeful with breakfast and it was a wonderful experience. It was delicious and the hotel was clean and welcoming.

2026-08-08 via Tripadvisor
E
Explore720117 Business
10
Highly Recommend!!
Pros:

I had a wonderful stay at the Residence Inn. From the moment I arrived, the staff was incredibly warm, hospitable, and attentive. The hotel was exceptionally clean, every need was met, and throughout my stay I could tell that the people who work here genuinely care about what they do and about the experience of their guests.

Breakfast was especially delightful and became one of the highlights of my stay. More than anything, I appreciated the hospitality of the entire staff. Being away from home can sometimes feel impersonal, but everyone here went above and beyond to create a welcoming and comfortable environment that truly made me feel cared for.

I will definitely stay here again whenever I am in Durham, and I would gladly recommend this Residence Inn to others. Thank you to the entire team for making my stay such a positive experience!

2026-08-08 via Tripadvisor
F
F4483PLkatm Business
10
5 star experience at business hotel prices
Pros:

definitely a business hotel that being said the staff from Ken (chef) to Kayla/Brad (shuttle) are very hospitable. Lowkey 5 star staff for a business hotel. Variety each day for breakfast and the Shuttle service is flexible/easy to use & the folks driving are accommodating and friendly as ever

2026-08-07 via Tripadvisor
D
davidsB1627AI Family
10
Don’t miss breakfast
Pros:

Ken is awesome! He hosts a great breakfast.

2026-08-07 via Tripadvisor
6
674lod Family
10
The Residence Inn in Durham provides excellent accommodations near Duke University Hospital
Pros:

When my husband underwent surgery for a liver transplant we discovered the Residence Inn-McPherson-Duke in Durham for an extended stay to be near Duke Hospital. It’s great that they have a shuttle service to go to appointments. Ken, the chef does an excellent job with a wonderful breakfast buffet. Deasia has been helpful as well at the front desk and her attitude and bright disposition makes one feel part of a family. In fact all of the staff are friendly and accommodating. I would recommend the Residence Inn for anyone needing comfortable accommodations near Duke Hospital!

2026-08-06 via Tripadvisor
S
seanbF5306MJ Business
10
Business stay August 2926
Pros:

My stay thus far has been great. The entire staff has been nothing short of accommodating and gracious. Special mention to Ken in the kitchen for consistent friendly and professional service!

2026-08-06 via Tripadvisor
W
W8533MFdanj Solo travel
10
Happy Ride
Pros:

Kayla is such a nice and friendly person. She had everyone laughing and joking on our drive to Duke.

2026-08-06 via Tripadvisor
3
301tashaw Business Seattle, Washington
10
Wonderful!
Pros:

Great driver. Very friendly.

2026-08-06 via Tripadvisor
K
K8630FZpamelas Family
10
Best staff; great breakfast buffet
Pros:

Great place to stay after medical treatment at Duke. Comfortable rooms and lots of amenities on-site. Best feature, though, is their staff! Everyone is so helpful and pleasant. Front desk receptionists took care of every request with a smile. Ken cooked up a wonderful buffet breakfast each day and greeted everyone with a smile. His crustless quiche was delicious! Will stay here again without hesitation.

2026-08-06 via Tripadvisor
C
chrishT4309JB Family
10
great stay, would recommend!
Pros:

Everyone was really nice! Buffet was great

2026-08-05 via Tripadvisor
B
bbclubm Family
10
Friendly staff, and nice rooms.
Pros:

The death of this hotel was very friendly.Deniasia was really helpful when I checked in late at night. The rooms were very nice and new. Great location if you’re going to the university.

2026-07-20 via Tripadvisor
J
Jordan family_with_children us
1
Cons:

There was hardly anyone working and it was difficult to get in touch with the front desk. Gave us a queen when we reserved a king and tried to argue that it was a king. Also gave us a pack and play, not a crib, that was very dirty with just a hotel sheet folded in the bottom.

2026-07-19 via Nuitee
I
I4541GLamym Family Charlotte, North Carolina
8
Good Stay
Pros:

We stayed here for a few days last month while my son attended a camp at Duke. Our room was spacious and clean. The parking situation can be difficult depending on what time you arrive. There were no garage spots or lot spots so we just parked across the street, it seems they are doing contruction to make that a larger lot. Breakfast ends at 9am which would be great to extend till 10. All the hotel employees we encountered were extremely friendly. If you are a light sleeper they mention having sound machines due to the train noise. It didn't really bother us. We were able to walk to quite a few restaurants in the area that were great. All in all I would choose this spot again.

2026-07-02 via Tripadvisor
H
hotelcritic00876 Family New York City, New York
2
A Masterclass in Hostility
Pros:

Most hotels train their staff in hospitality. The Residence Inn Durham appears to be the product of an accidental registration for the "open hostility" seminar and a game-time decision to fully commit to the curriculum. The staff here have a shocking commitment to discourtesy and everyone we encountered seemed genuinely offended by the presence of guests.

The room itself had the exhausted ambiance of a regional airport lounge. Every surface suggested a long-standing disagreement with disinfectant and carpets appeared to have absorbed several economic downturns. The “kitchen” featured the fun and exciting challenge of discovering which appliances/utensils still qualified as functional. Most did not.

If you’ve ever wondered what the complete philosophical rejection of housekeeping looks like, look no further than this hotel. Management cites “COVID-19” as their justification for not cleaning rooms. While I understand that some hotels offer the option (keyword OPTION!) to forgo daily cleaning services during longer stays, invoking pandemic protocol to avoid replacing towels for 4+ days in 2026 is quite bold.

The parking situation deserves academic study. You pay for parking, but not in the charmingly old-fashioned sense where your car remains near the hotel. Instead, the hotel invites you to on an odyssey to their auxiliary lot. Despite what they may tell you it is not close or convenient, particularly in the rain.

In fairness, the hotel did succeed in one respect: it inspired immediate brand loyalty to every competing property within The Triangle.

2026-05-26 via Tripadvisor
Y
Yury solo_traveller us
9
2026-05-01 via Nuitee
1
160marcusy Business
10
Wonderful experience!
Pros:

I had a wonderful experience here, even though it was only for a day. Tiffani at the front desk made the experience well worth it. She was very informative and offered excellent customer service.

2026-04-17 via Tripadvisor
E
Elly couple nl
9
2026-04-06 via Nuitee